Article: Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice.
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Tamagnini F; Novelia J; Kerrigan TL; Brown JT; Tsaneva-Atanasova K; Randall AD
Front Cell Neurosci, 2015
Resonance properties of CA1-PCs in hippocampal slices from 20 to 23 month old PDAPP mice and age-matched WT littermate controls.
|
WT n = 26 |
PDAPP n = 30 |
Property |
Average |
SEM |
Average |
SEM |
p |
Peak frequency (Hz) |
3.73 |
0.37 |
3.77 |
0.28 |
0.93 |
Q |
1.11 |
0.02 |
1.11 |
0.01 |
0.86 |
Peak Z (MΩ) |
90.34 |
9.45 |
100.99 |
7.90 |
0.39 |
Inferred neuron-electrophysiology data values
Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |